A Potential New Herpes Vaccine

The scourge of herpes has been with mankind since the days of ancient Greece, and despite many attempts to find a definitive cure, no vaccine to date has successfully been developed and made available to the public.

While there are many preventative measures people can take to minimise future genital herpes outbreaks, a one stop solution still remains beyond our grasp.

However, good news may be on the horizon. The U.S. National Institute of Health announced in 2013 that it will sponsor a clinical trial for a genital herpes vaccine. News of initial trial results are beginning to be reported and the great news, the initial trial results are proving positive.

The possible new vaccine is focused around the protein sub unit vaccine, GEN-003, which is under development by Genocea Biosciences Inc. This vaccine candidate is designed to manipulate the immune response of T cells. T cells are a form of white blood cell in the human body which attack pathogens, ie viruses and are an important defense mechanism the body has against infections.

So, put it into plain English, the new potential vaccine stimulates our immune system to attack and destroy the herpes virus. Well, while this of course comes as welcome news to the millions of genital herpes sufferers worldwide, it is important to remember that this research is still in its infancy. However, initial findings have proved positive.

The first initial test results showed that out of 143 human test subjects who had moderate to frequent genital herpes outbreaks, 51% had reductions in the frequency of viral shedding. The vaccine was administered to the test subjects via an IM (In muscle) injection into the patients' arm.

The research results are have so far shown that GEN-003 is proving to be a good starting point in understanding how the vaccine reduces viral shedding. Now, further research will need to be conducted to explore its potential.

I believe this is rather encouraging news. While it is early days in the research program, the fact that something positive is being reported is most welcome and provides a foundation on which the scientists can build on. It could be many months or even a few years before a definitive, proven vaccine is developed and made available to the general public. However, this news is already providing hope that one day, in the not too distant future, a genital herpes vaccine may be available to us all.

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